[New post] In Down Syndrome Cells, Genome-Wide Disruptions Mimic a Senescence-Like State

Mindzilla posted: " Cambridge, MA — In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disruption of gene transcription and cell " New post on Mindzilla® In Down Syndrome Cells, Genome-Wide Disruptions Mimic a Senescence-Like State by Mindzilla Cambridge, MA — In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disruption of gene transcription and cell function are so similar to those seen in cellular ageing, or […] Read more of this post Mindzilla | January 6, 2022 at 4:54 pm | Tags: Chromosomal introversion, Down Syndrome, Down Syndrome Cells, neural progenitors, senescence | Categories: Bioresearch, Cell Biology, Genomics, Neuroscience | URL: https://wp.me/pa6vSf-djN Comment    See all comments Unsubscribe to no longer receive posts from Mindzilla®. Change your email settings at Manage Subscriptions. Trouble clicking? Copy and paste this URL into your browser: https://mindzilla.com/newsroom/science/bioresearch/51199/20220106-in-down-syndrome-cells-genome-wide-disruptions-mimic-a-senescence-like-state/