In medicine, don't believe what someone says at face value. Make sure you do your research before you buy something. It's also important to know about the kidneys, so this is the book you need to have. This book, Comprehensive Clinical Nephrology PDF, is the best way to learn about and treat hypertension, AKI, CKD, diabetes with CKD, and even hyperlipidemia with CKD.

People who say, "What's the serum creatinine?" when deciding if someone should have IV contrast aren't telling the truth because it's just one of many factors that can cause AKI after IV contrast, such as age and multiple comorbidities. The fundamental determinant is eGFR; if you don't believe me, read this comprehensive Clinical Nephrology book.

The text doesn't say which BP level you should treat, the JNC 8, or the AHA guidelines. The text talks about each suggestion and why each one came to its conclusion, so you can understand why they did. So don't believe anyone who says, "Use the AHA guidelines because they're more up to date." When I hear that, I know that the person talking hasn't read the study.

AHA said there wasn't enough data on great studies, so they combined data from several not-perfect studies. JNC8 used the best studies. It's because medicine is an art, not just a science. Every person is different, and you need to know the rules before you start to do them.

To download the comprehensive Clinical Nephrology PDF, 6th edition, please follow the link provided below!

Comprehensive Clinical Nephrology PDF

The writers of Comprehensive Clinical Nephrology PDF, sixth edition, continue to provide a text for fellows, practicing nephrologists, and internists covering all areas of the nephrologist's clinical work, including fluids and electrolytes, hypertension, diabetes, dialysis, and transplantation.

True, this single volume cannot compete with multivolume or highly referenced online texts. Still, the goal remains to provide "comprehensive" coverage of clinical nephrology while also ensuring that inquiring nephrologists can find the key scientific issues and pathophysiology that underpin their clinical work.

All chapters have been significantly rewritten and updated in response to suggestions and comments from numerous readers and colleagues.

These revisions include the most recent discoveries, such as new insights into complement-mediated glomerular disorders and the most recent data on the prevalence and implications of acute kidney injury and renal replacement therapy.

A chapter on the rising problem of endemic nephropathies in low and medium-income countries is included.

This edition maintains the book's popular algorithmic style to emphasize different components of the material provided:

  • Yellow boxes for general information.
  • Blue boxes for necessary investigations.
  • Green boxes for treatments.

Due to popular demand, they will continue to provide readers with access to the book's photos. We are thrilled to see them being used in lectures and seminars worldwide.

This third edition includes access to an Expert Consult website with fully searchable text, a downloadable image collection, and PubMed links. This edition Comprehensive Clinical Nephrology PDF consists of an online question bank with over 400 multiple-choice questions.

Features of Comprehensive Clinical Nephrology PDF

World-class nephrologists wrote and edited the sixth edition of Comprehensive Clinical Nephrology. It includes the most recent information on how to do things in the real world and scientific facts about kidney disease and pathophysiology that are important for nephrologists to know and use in their work. It's excellent for nephrologists, internists, and fellows because it covers fluids and electrolytes, hypertension, diabetes, dialysis, transplantation, and more in a single, easy-to-read book.

  • A "just right" mix of basic science and clinical advice helps you make quick and intelligent decisions.
  • More than 1,500 full-color illustrations highlight essential topics and explain the pathogenesis of many kidney problems and how to treat them in the clinic.
  • New quick-reference boxes with links to clinical guidelines have been added to all chapters that deal with the subject.
  • There are new chapters on common issues with prescribing in kidney disease, palliative medicine, endemic nephropathies, the pathophysiology of chronic kidney disease, and the results of dialysis.
  • The eBook version of Expert ConsultTM comes with your purchase. If you have an upgraded e-book version, you can search all of the book's text, figures, and references on a wide range of different devices.

Contents

SECTION I Essential Renal Anatomy and Physiology

1 Renal Anatomy, 1

2 Renal Physiology, 14

SECTION II Investigation of Renal Disease

3 Assessment of Glomerular Filtration Rate, 29

4 Urinalysis, 39

5 Imaging, 53

6 Renal Biopsy, 72

SECTION III Fluid and Electrolyte Disorders

7 Disorders of Extracellular Volume, 80

8 Disorders of Water Metabolism, 94

9 Disorders of Potassium Metabolism, 111

10 Disorders of Calcium, Phosphate, and Magnesium Metabolism, 124

11 Normal Acid-Base Balance, 142

12 Metabolic Acidosis, 149

13 Metabolic Alkalosis, 160

14 Respiratory Acidosis, Respiratory Alkalosis, and Mixed Disorders, 170

SECTION IV Glomerular Disease

15 Introduction to Glomerular Disease: Clinical Presentations, 184

16 Introduction to Glomerular Disease: Histologic Classification and Pathogenesis, 199

17 Minimal Change Disease, 209

18 Primary and Secondary (Non-Genetic) Causes of Focal and Segmental Glomerulosclerosis, 219

19 Inherited Causes of Nephrotic Syndrome, 232

20 Membranous Nephropathy, 240

21 Membranoproliferative Glomerulonephritis and Cryoglobulinemic Glomerulonephritis, 254

22 Glomerulonephritis Associated With Complement Disorders, 263

23 Immunoglobulin A Nephropathy and IgA Vasculitis (Henoch-Schönlein Purpura), 270

24 Anti–Glomerular Basement Membrane Disease and Goodpasture Disease, 281

25 Renal and Systemic Vasculitis, 290

26 Lupus Nephritis, 306

27 Renal Amyloidosis and Glomerular Diseases With Monoclonal Immunoglobulin Deposition, 320

28 Rare Glomerular Disorders, 333

29 Thrombotic Microangiopathies, Including Hemolytic Uremic Syndrome, 343

SECTION V Diabetic Kidney Disease

30 Pathogenesis, Clinical Manifestations, and Natural History of Diabetic Kidney Disease, 357

31 Prevention and Treatment of Diabetic Kidney Disease, 376

32 Management of the Diabetic Patient With Chronic Kidney Disease, 385

SECTION VI Hypertension

33 Normal Blood Pressure Control and the Evaluation of Hypertension, 396

34 Primary Hypertension, 412

35 Nonpharmacologic Prevention and Treatment of Hypertension, 422

36 Pharmacologic Treatment of Hypertension, 430

37 Evaluation and Treatment of Hypertensive Emergencies and Urgencies, 444

38 Endocrine Causes of Hypertension: Aldosterone, 453

39 Other Endocrine Causes of Hypertension, 463

40 Neurogenic Hypertension, Including Hypertension Associated With Stroke or Spinal Cord Injury, 473

SECTION VII Renovascular Disease

41 Renovascular Hypertension and Ischemic

Nephropathy, 482

SECTION VIII Pregnancy and Renal Disease

42 Renal Physiology and Complications in Normal Pregnancy, 502

43 Pregnancy With Preexisting Kidney Disease, 522

SECTION IX Hereditary and Congenital Diseases of the Kidney

44 Autosomal Dominant Polycystic Kidney Disease, 532

45 Other Cystic Kidney Diseases, 545

46 Alport Syndrome and Other Familial Glomerular Syndromes, 560

47 Inherited Disorders of Sodium and Water Handling, 575

48 Fanconi Syndrome and Other Proximal Tubule Disorders, 586

49 Sickle Cell Diseases and the Kidney, 597

50 Congenital Anomalies of the Kidney and Urinary Tract, 607

SECTION X Infectious Diseases and the Kidney

51 Urinary Tract Infections in Adults, 626

52 Tuberculosis of the Urinary Tract, 639

53 Fungal Infections of the Urinary Tract, 650

54 The Kidney in Schistosomiasis, 655

55 Glomerular Diseases Associated With Infection, 664

56 Human Immunodeficiency Virus Infection and the Kidney, 679

SECTION XI Urologic Disorders

57 Nephrolithiasis and Nephrocalcinosis, 689

58 Urinary Tract Obstruction, 704

59 Urologic Issues for the Nephrologist, 717

SECTION XII Tubulointerstitial and Vascular Diseases

60 Acute Interstitial Nephritis, 729

61 Primary Vesicoureteral Reflux and Reflux Nephropathy, 738

62 Chronic Interstitial Nephritis, 748

63 Endemic Nephropathies, 761

64 Myeloma and the Kidney, 767

SECTION XIII Renal Disease and Cancer

65 Onconephrology: Kidney Disease in Cancer Patients, 776

SECTION XIV Acute Kidney Injury

66 Pathophysiology and Etiology of Acute Kidney Injury, 786

67 Acute Kidney Injury in the Tropics, 802

68 Diagnosis and Clinical Evaluation of Acute Kidney Injury, 810

69 Epidemiology and Prognostic Impact of Acute Kidney Injury, 820

70 Prevention and Nondialytic Management of Acute Kidney Injury, 825

71 Dialytic Management of Acute Kidney Injury and Intensive Care Unit Nephrology, 838

72 Dialytic Management of Refractory Heart Failure, 852

73 Hepatorenal Syndrome, 859

SECTION XV Drug Therapy in Kidney Disease

74 Principles of Drug Therapy, Dosing, and Prescribing in Chronic Kidney Disease and Renal Replacement Therapy, 870

75 Common Issues in Prescribing in Kidney Disease and Renal Replacement Therapy, 880

76 Herbal and Over-the-Counter Medicines and the Kidney, 894

SECTION XVI Chronic Kidney Disease and the Uremic Syndrome

77 Epidemiology of Chronic Kidney Disease and Dialysis, 903

78 Pathophysiology of Disease Progression in Proteinuric and Nonproteinuric Kidney Disease, 913

79 Retarding Progression of Kidney Disease, 924

80 Clinical Evaluation and Management of Chronic Kidney Disease, 935

81 Cardiovascular Disease in Chronic Kidney Disease, 942

82 Anemia in Chronic Kidney Disease, 958

83 Other Blood and Immune Disorders in Chronic Kidney Disease, 967

84 Bone and Mineral Disorders in Chronic Kidney Disease, 979

85 Neurologic Complications of Chronic Kidney Disease, 996

86 Gastroenterology and Nutrition in Chronic Kidney Disease, 1002

87 Dermatologic Manifestations of Chronic Kidney Disease, 1013

88 Acquired Cystic Kidney Disease and Malignant Neoplasms, 1022

SECTION XVII Geriatric and Palliative Nephrology

89 Geriatric Nephrology, 1028

SECTION XVIII Dialytic Therapies

90 Approach to Renal Replacement Therapy, 1036

91 Vascular Access for Dialytic Therapies, 1050

92 Diagnostic and Interventional Nephrology, 1062

93 Hemodialysis: Principles and Techniques, 1073

94 Hemodialysis: Dialysis Prescription and Adequacy, 1082

95 Acute Complications During Hemodialysis, 1090

96 Peritoneal Dialysis: Principles, Techniques, and Adequacy, 1103

97 Complications of Peritoneal Dialysis, 1114

98 Extracorporeal Therapies for Drug Overdose and Poisoning, 1124

99 Plasma Exchange, 1132

SECTION XIX Transplantation

100 Immunologic Principles in Kidney Transplantation, 1141

101 Immunosuppressive Medications in Kidney Transplantation, 1154

102 Evaluation and Preoperative Management of Kidney Transplant Recipient and Donor, 1163

103 Kidney Transplantation Surgery, 1174

104 Prophylaxis and Treatment of Kidney Transplant Rejection, 1186

105 Medical Management of the Kidney Transplant Recipient: Infections and Malignancies, 1198

106 Medical Management of the Kidney Transplant Recipient: Cardiovascular Disease and Metabolic

Abnormalities, 1213

107 Chronic Allograft Injury, 1226

108 Recurrent Disease in Kidney Transplantation, 1236

109 Outcomes of Renal Transplantation, 1247

110 Pancreas and Islet Transplantation, 1258

111 Kidney Disease in Liver, Cardiac, Lung, and Hematopoietic Stem Cell Transplantation, 1272

SECTION XX Palliative Nephrology

112 Palliative Nephrology, 1282

Index, 1289

Authors

John Feehally, DM, FRCP
Professor of Renal Medicine
The John Walls Renal Unit
Leicester General Hospital
Leicester, United Kingdom

Jürgen Floege, MD, FERA
Professor of Medicine
Director
Division of Nephrology and Clinical Immunology
RWTH University of Aachen
Aachen, Germany

Marcello Tonelli, MD, SM, MSc, FRCPC
Associate Vice President (Research)
Department of Medicine
University of Calgary
Calgary, Alberta, Canada

Richard J. Johnson, MD
Professor of Medicine
Division Chief
Tomas Berl Professor of Nephrology
University of Colorado–Denver
Denver, Colorado, USA

Book Details

  • Book Name: Comprehensive Clinical Nephrology 6th Edition
  • Authors: Richard J. Johnson MD (Author), John Feehally DM FRCP (Author), Jurgen Floege MD FERA (Author), Marcello Tonelli MD SM FRCPC (Author)
  • Publisher: ‎ Elsevier; 6th edition (September 11, 2018)
  • Language: ‎ English
  • Hardcover: ‎ 1360 pages
  • ISBN-10: ‎ 032347909X
  • ISBN-13: ‎ 978-0323479097
  • Item Weight: ‎ 7.78 pounds
  • Dimensions: ‎ 8.8 x 2.2 x 11.1 inches

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