The study looked at the acute toxicity of glyphosate and its long-term effects on the muscles of juvenile Clarias gariepinus fish, as well as the use of L-ascorbic acid (vitamin C) to treat induced glyphosate residues in the fish's muscles to prevent glyphosate bioaccumulation and subsequent toxicity when consumed by humans.
Latin square as a study design.
Between December 2018 to April 2019, I studied in the Department of Fisheries and Aquaculture Management at Nnamdi Azikiwe University in Awka, Nigeria.
Methodology: To estimate the LC50 of both glyphosate (Delsate®) and Vitamin C (Kepro®), 48-hour acute toxicity experiments were performed on eight juveniles of C. gariepinus with a mean weight of 41.501.35g and a length of 20.750.43cm. The fish were then subjected to sub-lethal amounts of glyphosate for 91 days (control), 5.0, 10.0, and 15mgL-1, and then treated individually with 50 and 100 mgL-1 vitamin C for 7 days. A second group of fish was given glyphosate and vitamin C at the same time for 91 days. Gas chromatography was used to evaluate glyphosate residues in the fish muscles.
Delsate® and Kepro® had LC50s of 75 mgL1 and 175 mgL1, respectively. When compared to the control, mean levels of glyphosate maintained in muscles of fish exposed to glyphosate for 91 days increased significantly (P.05). Vitamin C therapy seven days after exposure reduced glyphosate residues in fish muscles significantly (P.05), with 100 mgL-1 vitamin C being more efficient than 50 mgL-1. On the muscles of C. gariepinus, the second set-up had no appreciable therapeutic benefits.
Conclusion: The LC50 of glyphosate and Vitamin C was found in this study. Treatment of affected fish in a water bath containing Vitamin C might render glyphosate residues in their muscles safe for human consumption. Our current research focuses on histopathological changes in tissues of juvenile C. gariepinus fish exposed to glyphosate.
Please click here : https://journalajfar.com/index.php/AJFAR/article/view/30174
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