PediatricDigest

PediatricDigest

Tuesday, 5 July 2022

[New post] Neonatal jaundice; causes, clinical assessment , PHYSIOLOGICAL VERSUS PATHOLOGICAL JAUNDICE

Site logo image interestingped5302 posted: " Neonatal jaundice is the most common cause morbidity in the first week of life. 60% of term newborns 80% of preterm newborns Neonatal jaundice is the most common cause of re-admission after discharge from birth hospitalization. In neonates is when total" Interesting pediatric topic

Neonatal jaundice; causes, clinical assessment , PHYSIOLOGICAL VERSUS PATHOLOGICAL JAUNDICE

interestingped5302

Jul 5

  • Neonatal jaundice is the most common cause morbidity in the first week of life.
    • 60% of term newborns
    • 80% of preterm newborns
  • Neonatal jaundice is the most common cause of re-admission after discharge from birth hospitalization.
    • In neonates is when total serum bilirubin (TSB) concentration exceeds 5 to 7 mg/dL.
      • visible in skin
      • eyes
    • In adults have jaundice visible in eyes when TSB concentration exceeds 2 mg/dL.
  • Increased TSB concentration in neonate results from
    1. increased production
    2. decreased clearance and
    3. re-absorption

PHYSIOLOGICAL VERSUS PATHOLOGICAL JAUNDICE

  • Jaundice attributable to physiological immaturity of neonates to handle increased bilirubin production is termed as physiological jaundice .
  • 'Pathological jaundice' is said to be present when TSB concentrations are not in physiological jaundice .
Presence of one or more of the following conditions would qualify a neonate to have pathological jaundice
  • Common causes of pathological jaundice in neonate include:
    • Hemolysis
    • Decreased conjugation
    • Increased enterohepatic circulation
    • Extravasated blood

Hemolysis

  • Blood group incompatibility
  • enzyme deficiencies
  • autoimmune hemolytic anemia

Decreased conjugation

  • Due to liver enzyme immaturity

Increased enterohepatic circulation

  • Lack of adequate enteral feeding that includes insufficient breastfeeding or the infant not being fed because of illness, GI obstruction

Extravasated blood

  • Cephalhematoma, extensive bruising increased the risk of neonatal jaundice.

CLINICAL ASSESSMENT

The parents should be counselled.

Visual inspection of neonatal jaundice.

Visual inspection of neonatal jaundice

Inadequacy of breastfeeding is a common cause of exaggerated jaundice during initial few days (breastfeeding jaundice).

All neonates should be examined at every opportunity but not lesser than every 12 hr until first 3 to 5 days of life for jaundice.

At higher risk of jaundice should be identified.

Higher risk of neonata jaundice

Indications of TSB Measurement in neonatal jaundice

  • Jaundice in first 24 hours.
  • Beyond 24 hrs: If visually assessed, jaundice is likely to be more than 12 to 14 mg/dL (as visual assessment becomes unreliable) beyond this TSB level or approaching the phototherapy range or beyond.
  • Unsure about visual assessment.
  • During phototherapy.
Comment

Unsubscribe to no longer receive posts from Interesting pediatric topic.
Change your email settings at manage subscriptions.

Trouble clicking? Copy and paste this URL into your browser:
https://interestingped.com/2022/07/05/neonatal-jaundice-causes-clinical-assessment-physiological-versus-pathological-jaundice/

Powered by WordPress.com
Download on the App Store Get it on Google Play
at July 05, 2022
Email ThisBlogThis!Share to XShare to FacebookShare to Pinterest

No comments:

Post a Comment

Newer Post Older Post Home
Subscribe to: Post Comments (Atom)

Latest from Food Politics: Oops. District Court in DC says USDA's state SNAP waivers are illegal

Yesterday, a US District Court in the District of Columbia ruled that the USDA violated its own laws when it approved SNAP food restrictio...

  • PowKids Clean Protein: Raising Powerful Kids!
    Photo courtesy of PowKids! I received samples of Powkids protein ($79.98 valu...
  • Latest from Food Politics: Weekend reading: Flagstaff anti-hunger efforts
    In September 2025, I was invited by the Flagstaff Family Food Center to give a talk on “Anti-Hunger Politics 2025: Planting Seeds for Resi...
  • Does Lauren Boebert have her GOP primary locked up — or will a lesser-known candidate break out?
    Money. Incumbency. Near-universal name recognition.U.S. Rep. Lauren Boebert [cq ...

Search This Blog

  • Home

About Me

PodiatryDigest
View my complete profile

Report Abuse

Blog Archive

  • June 2026 (23)
  • May 2026 (31)
  • April 2026 (31)
  • March 2026 (31)
  • February 2026 (29)
  • January 2026 (29)
  • December 2025 (32)
  • November 2025 (29)
  • October 2025 (33)
  • September 2025 (33)
  • August 2025 (36)
  • July 2025 (40)
  • June 2025 (24)
  • May 2025 (17)
  • April 2025 (16)
  • March 2025 (16)
  • February 2025 (11)
  • January 2025 (6)
  • December 2024 (8)
  • November 2024 (8)
  • October 2024 (8)
  • September 2024 (1481)
  • August 2024 (1712)
  • July 2024 (2057)
  • June 2024 (2105)
  • May 2024 (2319)
  • April 2024 (2069)
  • March 2024 (2286)
  • February 2024 (2422)
  • January 2024 (2539)
  • December 2023 (1955)
  • November 2023 (1449)
  • October 2023 (1186)
  • September 2023 (1072)
  • August 2023 (826)
  • July 2023 (771)
  • June 2023 (793)
  • May 2023 (829)
  • April 2023 (707)
  • March 2023 (753)
  • February 2023 (673)
  • January 2023 (752)
  • December 2022 (706)
  • November 2022 (731)
  • October 2022 (701)
  • September 2022 (694)
  • August 2022 (716)
  • July 2022 (752)
  • June 2022 (845)
  • May 2022 (1011)
  • April 2022 (1138)
  • March 2022 (596)
  • February 2022 (423)
  • January 2022 (449)
  • December 2021 (581)
  • November 2021 (1495)
  • October 2021 (1539)
  • September 2021 (1455)
  • August 2021 (196)
Powered by Blogger.