The goal of this study was to see if an ethanol extract prepared from Boswellia dalzielii stem bark has antiproliferative effect in breast cancer.
Methodology: An ethanolic extract of Boswellia dalzielii stem bark was made. The antiproliferative activity of 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide in oestrogen receptor (ER)-negative breast cancer (MDA-MB-231) cells was determined using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay.
The ethanol extract of Boswellia dalzielii stem bark demonstrated considerable antiproliferative action in MDA-MB-231 cells in a dose-dependent manner, according to the results of the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide test. In MDA-MB231 cells, the IC50 of Boswellia dalzielii stem bark ethanol extract was 98.12 g/mL.
Conclusion: The findings imply that Boswellia dalzielii stem bark extract has substantial antiproliferative properties, which might be mediated by the plant's chemical contents. However, further study is needed to identify the extract's effect on the cell cycle as well as the sort of cell death it causes.
Please click here : https://journaljocamr.com/index.php/JOCAMR/article/view/30180
No comments:
Post a Comment