Background: In Egypt, hemodialysis (HD) is the most common form of RRT, and it is a significant financial burden on the health-care system. In Egypt's Alexandria province, HD service is offered through fifty-seven HD units, twenty-one of which are nonprofit and thirty-six of which are private for-profit. Our goals were to investigate the epidemiology and estimate the three-year survival of ESRD patients treated with HD in Alexandria province's government facilities.
Methods and Design: Patient data were obtained in 2016 from all governmental hospitals in Alexandria province, which included seven HD units with a total of 687 patients. Demographic data, vascular access, HIV, HBV, and HCV serology, the potential aetiology of chronic kidney disease (CKD), related comorbidities, and regular laboratory variables were all included in a cross-sectional arm of the study. A three-year survival rate of the examined HD patients was also reported in a prospective phase of the trial.
The overall number of HD patients in Alexandria province in 2019 was 3552 in all HD units, resulting in an estimated HD prevalence rate of roughly 710 ppm. The 687 patients in the governmental HD facilities who were polled had a mean age of 50.78 years, with more males, and a mean duration of HD of 55 months. There was also no evidence of positive seroconversion to HCV, HBV, or HIV. Sixteen HCV antibody-positive individuals were treated with direct-acting antiviral medications and were subsequently PCR-negative for HCV. Males had a higher prevalence of HTN, whereas females had a higher prevalence of DM and combined DM and HTN. In around 37% of the HD patients evaluated, the goal haemoglobin level was present. The majority of the patients had blood calcium levels between 8 and 10 mg/dl, while 53% had serum phosphorus levels between 3-5.5 mg/dl. A para-thyroidectomy was performed in 2% of the instances investigated, whereas cinacalcet was used in 4% of the cases. The survival rates were 92.5 percent, 87 percent, and 82 percent after three, five, and seven years, respectively.
Conclusion: The epidemiology of hemodialysis patients in Alexandria province is similar to that of other Egyptian governorates in many ways, although no new epidemiology for the entire nation has been published. After following the antiviral therapy approach, 11.2 percent of HCV Abs positive patients turned PCR negative.
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